FORTE BIO RED96E STATIC SMOOTH DRUM ROLLER

Technical Description

The ForteBio RED96e Static Smooth Drum Roller is a high-performance biosensor platform optimized for label-free, real-time biomolecular interaction analysis using Bio-Layer Interferometry (BLI) technology. It supports the use of a standard 96-well black, flat-bottom microplate with a sample volume of 180–220 µL per well in a non-destructive testing format. The system accommodates up to eight independent channels, allowing simultaneous analysis of multiple samples. It operates within an analysis temperature range of 15–40°C, adjustable in 1°C increments, and offers orbital shaking speeds from static to 100–1500 rpm to ensure optimal assay conditions. The instrument's sensitivity enables detection of molecules with molecular weights above 150 Da and provides affinity constant interpretation within a broad dynamic range (KD 1 mM to 10 pM). Baseline noise remains low at ≤ 3.5 pm (RMS), with minimal baseline drift of ≤ 0.1 nm/hour, ensuring precise kinetic and affinity measurements. It facilitates rapid quantitation and kinetic analysis of protein binding, such as human IgG detection from 0.05 to 2000 µg/mL. The compact footprint measures approximately 19.5 x 22 x 18.2 inches (H x W x D) and weighs 72 lb. Electrical requirements are mains 100–120/200–240 VAC, 50/60 Hz, with a maximum current of 4 A and power consumption of 200 W (300 W peak). This system is widely used for antibody characterization, epitope binning, protein-small molecule interaction screening, and bioprocess optimization, supporting high-throughput workflows in biopharmaceutical and research laboratories.